Neurotrophins Live or Let Die: Does p75NTR Decide?

However, enhancing neurotrophin binding is not the Cornell University Medical College only role for p75. A number of reports suggest that it New York, New York 10021 also modulates trk signaling. While it is clear that trk †Growth Factor and Regeneration Group signaling can occur in the absence of p75, the reDepartment of Neuroscience sponses are increased in its presence. For example, Max Delbrück Institute for Molecular Medicine sympathoadrenal cells (MAH cells) expressing only trkA Berlin-Buch D-13122 extended neurites and survived in the presence of NGF Federal Republic of Germany but when coexpressing p75 showed an 8-fold higher